Hyperaldosteronism is an endocrine disorder that involves one or both of your adrenal glands creating too much of a hormone called aldosterone.
This causes your body to lose too much potassium and retain too much sodium, which increases water retention, blood volume, and blood pressure.
What happens when you have too much aldosterone?
In hyperaldosteronism, overproduction of aldosterone leads to fluid retention and increased blood pressure, weakness, and, rarely, periods of paralysis. High aldosterone levels can cause high blood pressure and low potassium levels.
What causes elevated aldosterone levels?
The most common cause of high aldosterone levels is excess production, frequently from a small benign adrenal tumour (primary hyperaldosteronism). The symptoms include high blood pressure, low blood levels of potassium and an abnormal increase in blood volume.
How do you treat high aldosterone levels naturally?
Confirming the diagnosis is done by temporarily increasing the amount of sodium in the body, either with a high-sodium diet or an infusion of sodium-rich salt water. When the adrenal glands are working correctly, this should turn down aldosterone production. When they aren’t, aldosterone levels remain high.
What are the signs and symptoms of Conn’s syndrome?
Signs and Symptoms of Hyperaldosternoma / Conn’s Syndrome
- muscle weakness.
How do you treat high levels of aldosterone?
Medication. Your doctor might prescribe a mineralocorticoid receptor antagonist, such as spironolactone. This type of medication blocks the effects of aldosterone on your body, such as high blood pressure and low blood potassium. You may still need to take additional medications to help manage your blood pressure.
Can stress cause high aldosterone levels?
Psychological stress also activates the sympathetic-adrenomedullary system which stimulates rennin release leading to increases in angiotensin II and aldosterone secretion. Prospective cohort studies may be used to consider effects of chronic stress on aldosterone and changes in aldosterone levels over time.
What are the symptoms of too much aldosterone?
In hyperaldosteronism, overproduction of aldosterone leads to fluid retention and increased blood pressure, weakness, and, rarely, periods of paralysis. Hyperaldosteronism can be caused by a tumor in the adrenal gland or may be a response to some diseases.
What does too much aldosterone do?
Usually, aldosterone balances sodium and potassium in your blood. But too much of this hormone can cause you to lose potassium and retain sodium. That imbalance can cause your body to hold too much water, increasing your blood volume and blood pressure.
Does high aldosterone cause weight gain?
Fast-growing tumors sometimes cause the adrenal gland to produce elevated levels of aldosterone, cortisol, and adrenal sex hormones such as androgen. Symptoms of adrenocortical carcinoma—such as high blood pressure, weight gain, and diabetes—can easily be attributed to or confused with many other medical problems.
Is Conn’s Syndrome serious?
Conn’s syndrome is a condition associated with the development of high blood pressure in the presence of low potassium levels in the blood. In some patients, the abnormal function of the adrenal cortex results from a less serious condition called adrenal hyperplasia.
What triggers the release of aldosterone?
If decreased blood pressure is detected, the adrenal gland is stimulated by these stretch receptors to release aldosterone, which increases sodium reabsorption from the urine, sweat, and the gut. This causes increased osmolarity in the extracellular fluid, which will eventually return blood pressure toward normal.
What is the most common cause of hyperaldosteronism?
Pathophysiology. Primary hyperaldosteronism occurs due to the excess production of the adrenal gland. The most common cause in two-thirds of the patients occurs due to idiopathic bilateral adrenal hyperplasia.