Diseases Caused By Streptococcus Pyogenes?


pyogenes can asymptomatically colonize humans, and may cause invasive diseases, such as bacteremia, pneumonia, necrotizing fasciitis, and streptococcal toxic shock syndrome [1, 2].


pyogenes accounts for 2-5% of cases of bacterial pneumonia in the early 20th century [3].

What respiratory disease can be caused by Streptococcus pyogenes in rare cases?

pyogenes was a common cause of epidemic outbreaks and community-acquired pneumonia (CAP) [1–3]. Currently S. pyogenes is considered a rare cause of community acquired pneumonia, being a clinical entity seen only sporadically after an influenza infection [4–5].

Where is Streptococcus pyogenes found?

Epidemiology. S. pyogenes (group A β-hemolytic streptococcus) can be found in the oropharynx of more than 20% of children and a smaller percentage of adults.

Can Streptococcus pyogenes kill you?

pyogenes infections and rheumatic fever disease alone causes 233,000 deaths (8). 1,800 invasive S. pyogenes disease-related deaths are reported in the USA yearly, necrotizing fasciitis kills about 30% of patients and streptococcal toxic shock syndrome has a mortality rate of 30-70% (3, 11, 12).

What are the sequelae of Streptococcus pyogenes infection?

Acute Streptococcus pyogenes infections may take the form of pharyngitis, scarlet fever (rash), impetigo, cellulitis, or erysipelas. Patients may also develop immune-mediated sequelae such as acute rheumatic fever and acute glomerulonephritis.

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