Is Serratia marcescens harmful to human health?
Today, Serratia marcescens is considered a harmful human pathogen which has been known to cause urinary tract infections, wound infections, and pneumonia. Serratia is normally not harmful to healthy people but it is what is known as an opportunistic pathogen. Given the opportunity, Serratia can spell trouble.
Where is Serratia marcescens found in the human body?
Serratia marcescens accounts for only 1-2% of the nosocomial infections which are mostly confined to the respiratory tract, the urinary tract, surgical wounds and soft tissues. Meningitis, which is caused by Serratia marcescens, has been reported from the paediatrics wards.
Is Serratia marcescens common?
Once considered a harmless saprophyte, Serratia marcescens is now recognized as an important opportunistic pathogen combining a propensity for healthcare-associated infection and antimicrobial resistance. Of all Serratia species, S. marcescens is the most common clinical isolate and the most important human pathogen.
What are the symptoms of Serratia marcescens?
Approximately 30-50% of patients with Serratia urinary tract infections are asymptomatic. Symptoms may include fever, frequent urination, dysuria, pyuria, or pain upon urination. In 90% of cases, patients have a history of recent surgery or instrumentation of the urinary tract.
Can you die from Serratia marcescens?
In the 1970s, when the military disclosed the tests, a San Francisco family sued over a pneumonia death they blamed on Serratia. Today, Serratia marcescens is considered a harmful human pathogen which has been known to cause urinary tract infections, wound infections, and pneumonia.
What Antibiotics kill Serratia marcescens?
marcescens were treated with ceftriaxone, kanamycin, gentamicin, and chloramphenicol at doses corresponding to 10, 100 and 1000 times their planktonic minimum inhibitory concentration. In addition, biofilms were also treated with chemical compounds such as polysorbate-80 and ursolic acid. S.
How do you kill Serratia marcescens?
Scrub the biofilm off of hard shower surfaces.The stubborn biofilm of Serratia marcescens can only be removed through agitation and elbow grease. Start by mixing up a slightly runny paste consisting of a quarter-cup baking soda and a tablespoon of liquid dish soap in a small bowl.
What is the best treatment for Serratia marcescens bacteria?
Serratia infections should be treated with an aminoglycoside plus an antipseudomonal beta-lactam, as the single use of a beta-lactam can select for resistant strains. Most strains are susceptible to amikacin, but reports indicate increasing resistance to gentamicin and tobramycin.
What is unique about Serratia marcescens?
marcescens notable in the world of antibiotic resistance. Beyond chromosomal-mediated resistance, it also has the ability to acquire resistance mechanisms from other bacteria and is intrinsically resistant to penicillin G, clindamycin, macrolides, glycopeptides, linezolid, and rifampin. Most isolates of S.