Why would defective collagen proteins affect joints?
This means that your immune system mistakenly attacks your body’s healthy tissue.
No one knows what causes your immune system to do this.
The attacks usually cause inflammation.
If you have a collagen vascular disease, your immune system causes inflammation in your collagen and nearby joints.
Which disease results the breakdown of collagen?
Ehlers-Danlos syndrome – Refers to the progressive deterioration of collagen most commonly due to mutations in COL5A1 or COL5A2 gene.
What are collagen vascular diseases?
Collagen vascular diseases are autoimmune diseases that occur when the body’s immune system attacks its own skin, tissues and organs. It may also eventually affect joints and organs such as skin, liver and kidneys. Other forms of connective tissue disease: Dermatomyositis. Morphea.
How is collagen vascular disease diagnosed?
Diagnosing collagen vascular diseasesBlood tests: Your blood sample will be analyzed for hormone levels and the presence of other diseases that may lead to infertility. Urinalysis: Your urine will be checked for the presence of infection, blood or increased protein.