In conclusion, consanguineous marriage is significantly higher in many genetic diseases which suggests that couples may have deleterious lethal genes, inherited from common ancestor and when transmitted to their offsprings, they can lead to prenatal, neonatal, child morbidity or mortality.
Why are consanguineous marriages discouraged?
In communities with high consanguinity rates, sociological studies indicate that consanguineous marriage could enforce the couples’ stability due to higher compatibility between husband and wife who share the same social relationships after marriage as before marriage, as well as the compatibility between the couple
What is consanguinity Why is an autosomal recessive disorder more likely to result from consanguinity?
The degree of relatedness between two individuals defines the proportion of genes shared between them. The offspring of consanguineous couples are at increased risk for autosomal recessive disorders due to their increased risk for homozygosity by descent.
What is consanguinity in genetics?
In clinical genetics, consanguinity is defined as a union between two individuals who are related as second cousins or closer, with the inbreeding coefficient (F) equal or higher than 0.0156.
Can first cousins have a healthy baby?
They say there is no biological reason to discourage cousins from marrying. First cousins are somewhat more likely than unrelated parents to have a child with a serious birth defect, mental retardation or genetic disease, but their increased risk is nowhere near as large as most people think, the scientists said.